METAPLASTIC BREAST CARCINOMA

CASE SERIES

Authors

  • Fergus Tomás Rocha de Oliveira Universidade Estadual do Piauí
  • Rafael Everton Assunção Ribeiro da Costa Universidade Estadual do Piauí
  • Eduarda Norberto Siqueira Universidade Estadual do Piauí
  • Ana Lúcia Nascimento Araújo Hospital São Marcos
  • Sabas Carlos Vieira Oncocenter

Keywords:

Medical Records, Breast Neoplasms, Recurrence, Neoplasm Metastasis

Abstract

Introduction: Metaplastic breast carcinoma (MBC) is understood as a heterogeneous group of malignant tumors, which exhibits the transformation of part or its entire glandular carcinomatous component into a nonglandular component by means of epithelial and mixed mesenchymal differentiation. The MBC is a rare and aggressive breast cancer, accounting for approximately 1% of all breast tumors that have a worse prognosis. The aim of this study was to describe four cases of MBC, analyzing the progression of patients in a mean follow-up of 25 months (11–43 months). Case series: All patients were female. The mean age of the four cases of the series was 50 years (40–61 years). All patients had tumors that were histologically classified as metaplastic carcinoma. The mean tumor size of the series was 8.3 cm (2.2–15.5 cm). Two patients had the angiolymphatic invasion, and none had the perineural invasion. In three cases, there was an axillary node involvement. None of the cases had metastasis at the time of diagnosis. All patients underwent surgical treatment. Concerning complementary treatment, all patients underwent chemotherapy, three underwent radiation therapy, and two received hormone therapy. Three patients had systemic recurrence with metastases (i.e., all progressed to death). The study was approved by a Research Ethics Committee, under CAAE Nº 30154720.0.0000.5209. Conclusion: With a mean follow-up of 25 months (11–43 months), three out of four cases (75%) presented systemic recurrence with metastases (i.e., all culminating in death), and one patient is alive without evidence of malignancy.

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Published

2021-10-14

How to Cite

Oliveira, F. T. R. de, Costa, R. E. A. R. da, Siqueira, E. N., Araújo, A. L. N., & Vieira, S. C. (2021). METAPLASTIC BREAST CARCINOMA: CASE SERIES. Mastology, 31, 75. Retrieved from https://revistamastology.emnuvens.com.br/revista/article/view/1048

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E-poster