BREAST CANCER IN YOUNG PATIENTS

PROGNOSTIC AND PROFILE EPIDEMIOLOGICAL ANALYSIS IN A TERTIARY HOSPITAL

Authors

  • Amilcar Alves Assis Hospital de Base do Distrito Federal
  • Mauro Passos Hospital de Base do Distrito Federal
  • Rodrigo Kouzak Hospital de Base do Distrito Federal
  • Karoline Evangelista Hospital de Base do Distrito Federal
  • Natasha Caldas Hospital de Base do Distrito Federal

Keywords:

Breast Cancer, Young Women, Premenopause

Abstract

Breast cancer is the second most prevalent and first in mortality in Brazilian women. Its incidence has increased in recent years in all age groups. According to the Instituto Nacional do Câncer in 2019, 59,700 new cases of breast cancer are expected, with an estimated risk of 56.33 cases per 100 women. The diagnosis of breast cancer is more frequent in women after 50 years of age; it is estimated that only 25% of all cases occur in women below the age of 50 years; however, there was a literature consensus that tumors in this young age group have a worse prognosis, both because they are biologically more aggressive and because of affect women outside the screening age group in Brazil; thus, the rate of locally advanced disease at diagnosis in this age group is considerably higher. It is suggested that early onset breast cancer is related to different etiological factors, histopathological aspects, and clinical outcomes, as compared to postmenopausal breast cancer. Thus, age becomes an important prognostic factor. Since breast cancer is a curable pathology, the type of therapeutic approach also varies, with proposed treatment tends to be more aggressive. With the advent and increasing availability of genetic tests, predisposition of breast cancer has increased the number of indications for prophylactic mastectomies, especially in younger age groups or notably in patients with known pathological mutations in BRCA1 and BRCA2 genes. However, the literature is still controversial regarding its impact on overall survival. Breast cancer diagnosed before the age of 50 years is a behavioral disease, with prognosis and approach very different from that diagnosed in postmenopausal women. Therefore, it is important to know the profile of these patients to provide optimal treatment and achieve the best outcomes.

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Published

2021-10-14

How to Cite

Assis, A. A., Passos, M., Kouzak, R., Evangelista, K., & Caldas, N. (2021). BREAST CANCER IN YOUNG PATIENTS: PROGNOSTIC AND PROFILE EPIDEMIOLOGICAL ANALYSIS IN A TERTIARY HOSPITAL. Mastology, 31, 94. Retrieved from https://revistamastology.emnuvens.com.br/revista/article/view/1067

Issue

Section

E-poster