Pleomorphic adenoma of the breast
Keywords:
adenoma, pleomorphic, breast neoplasms, neoplasms, glandular and epithelialAbstract
Pleomorphic adenoma (PA) is a common tumor of the salivary gland, but rarely occurs in the breast. PA of the breast is a benign tumor that usually presents as a periareolar nodule. Core-needle biopsies may yield misdiagnosis with complex fibroadenoma, phyllodes tumor and metaplastic breast cancer due to the mixture of stromal and epithelial elements. We present a case of PA of the breast suspected after core-needle biopsy, but confirmed after surgical excision. The importance to make a correct diagnosis consists in avoid extensive unnecessary surgery, such as mastectomy, since PA can be treated with local surgical resection.
Downloads
References
Reid-Nicholson M, Bleiweiss I, Pace B, Azueta V, Jaffer S. Pleomorphic adenoma of the breast: A case report and distinction from mucinous carcinoma. Arch Pathol Lab Med. 2003;127(4):474-7. https://doi.org/10.1043/0003-9985(2003)127%3C0474:paotb%3E2.0.co;2
John BJ, Griffiths C, Ebbs SR. Pleomorphic adenoma of the breast should be excised with a cuff of normal tissue. Breast J. 2007;13(4):418-20. https://doi.org/10.1111/j.1524-4741.2007.00452.x
Takahashi K. Diagnosis of an extremely rare pleomorphic adenoma of the breast with core needle biopsy: A case report. Ann Med Surg. 2018;36:242-5. https://doi.org/10.1016/j.amsu.2018.10.037
Djakovic A, Engel JB, Geisinger E, Honig A, Tschammler A, Dietl
J. Pleomorphic adenoma of the breast initially misdiagnosed as metaplastic carcinoma in preoperative stereotactic biopsy: a case report and review of the literature. Eur J Gynaecol Oncol. 2011;32(4):427-30.
Foschini MP, Krausz T. WHO Classification of Tumours. Breast Tumours. In: WHO Classification of Tumours Editorial Board, editor. WHO Classification of tumour series. 5th ed. Lyon: International Agency for Research on Cancer; 2019. p. 40-2.
Lecène AL. Observation d’un cas de tumeur “mixte” du sein. Rev Chir. 1906;33:434-68.
Khamechian T, Alizargar J, Mazoochi T. Reporting a Rare Case of Pleomorphic Adenoma of the Breast. Case Rep Med. 2014;2014:387183. https://doi.org/10.1155/2014/387183
Di Bonito M, Cantile M, Cerrone M, Liguori G, Botti G. Synchronous Pleomorphic Adenoma and Invasive Ductal Carcinoma in Distinct Breasts. Breast J. 2015;21(4):428-30. https://doi.org/10.1111/tbj.12426
Srinivasamurthy BC, Bhat RV, Gopal SV. A rare benign tumor of breast masquerading on fine needle aspiration cytology: A case report. Breast Dis. 2017;37(2):105-7. https://doi.org/10.3233/bd-170270
Nestarez JE, Corrêa MAC, Simöes AB, Cominotti MLM, Barreto E, Rosa JAV. Adenoma pleomórfico da mama. Rev Bras Mastol. 1998;8(3):164-6.
Leekha N, Muralee M, Mathews A, Preethi TR, Ahamed MI. Pleomorphic Adenoma of Breast-A Case Report and Review of Literature. Indian J Surg Oncol. 2014;5(2):152-4. https://doi.org/10.1007/s13193-014-0310-y
Arslan A, Güldoğan N, Kapucuoğlu N, Esen G, Kara H, Uras C. A rare case of pleomorphic adenoma of the breast: Ultrasonography and pathology findings. Breast J. 2018;24(6):1069-70. https://doi.org/10.1111/tbj.13133
Diaz NM, McDivitt RW, Wick MR. Pleomorphic adenoma of the breast: A clinicopathologic and immunohistochemical study of 10 cases. Hum Pathol. 1991;22(12):1206-14. https://doi.org/10.1016/0046-8177(91)90102-u
Sato K, Ueda Y, Shimasaki M, Ozaki M, Nitta N, Chada K, et al. Pleomorphic adenoma (benign mixed tumor) of the breast: A case report and review of the literature. Pathol Res Pract. 2005;201(4):333-9. https://doi.org/10.1016/j. prp.2005.03.004
Rakha EA, Aleskandarany MA, Samaka RM, Hodi Z, Lee AHS, Ellis IO. Pleomorphic adenoma-like tumour of the breast. Histopathology. 2016;68(3):405-10. https://doi.org/10.1111/his.12757
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Marina Sonagli, Georgia Terra Lustre di Flora, Tábata Alves Domingos, Vinicius Felipe Cardona, Solange Maria Torchia de Carvalho, Cynthia Aparecida Bueno de Toledo Osório, Fabiana Baroni Alves Makdissi

This work is licensed under a Creative Commons Attribution 4.0 International License.