Nutritional status and cardiovascular risk in women with breast cancer

Authors

Keywords:

breast neoplasms, nutritional status, obesity, lifestyle, ardiovascular diseases

Abstract

Objective: To evaluate the nutritional status and the cardiovascular risk in women with breast cancer and identify factors associated with excessive body weight. Methods: A descriptive, cross-sectional, quantitative study was carried out in an oncology outpatient clinic and, gynecology/oncology wards at the Hospital das Clínicas da Universidade Federal de Pernambuco, from March to August 2019. The data analyzed was related to sociodemographic, gynecologic, clinic, anthropometric and lifestyle factors. Nutritional status was assessed using Body Mass Index, considering excessive body weight when > 25 kg/m2 for adults and > 27 kg/m2 for elderly. Obesity was considered > 30 kg/m 2. Cardiovascular risk was defined by waist circumference (≥ 80 cm), neck circumference (≥ 34 cm) and waist-to-height ratio (> 0.5). Results: A total of 46 patients were included, with a mean age of 51.9 years, and the majority in outpatient follow-up. The population was mostly Caucasian women, who were married or in a civil union, who had had at least one pregnancy, were in menopause, and were sedentary. High frequencies of excessive body weight (76.1%) and obesity (43.5%) were observed, and anthropometric parameters revealed an elevated frequency of cardiovascular risk in this population, waist circumference (97.8%), neck circumference (84.8%), and waist-to-height ratio (95.7%). Unemployment (p = 0.020), and waist (p = 0.001) and neck (p = 0.001) circumferences were statistically associated factors to excessive body weight. Conclusions: The anthropometric profile of women with breast cancer indicated excess body weight and elevated cardiovascular risk, which suggests to the need for nutrition intervention and follow-up after the diagnosis.

Downloads

Download data is not yet available.

References

Instituto Nacional de Câncer José Alencar Gomes da Silva. Prevenção e Fatores de risco para o câncer de mama [Internet]. 2019 [accessed on May 6, 2020. Available from: https://www.inca.gov.br/tipos-de-cancer/cancer-de-mama/profissional-de-saude

Instituto Nacional de Câncer José Alencar Gomes da Silva. Estimativa 2020: incidência de câncer no Brasil. Brasil: Instituto Nacional de Câncer José Alencar Gomes da Silva; 2019.

American Society of Cancer; Merck. Global burden of cancer in women: current status, trends, and interventions [Internet]. World Cancer Congress. Paris; 2016 [accessed on Dec 8, 2018]. Available from: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/global-cancer-facts-and-figures/global-burden-of-cancer-in-women.pdf

Sofi NY, Jain M, Kapil U, Seenu V, Lakshmy R, Yadav CP, et al. Reproductive factors, nutritional status and serum 25(OH) D levels in women with breast cancer: A case control study. J Steroid Biochem Mol Biol. 2018;175:200-4. https://doi.org/10.1016/j.jsbmb.2017.11.003

Rezende LFM, Arnold M, Rabacow FM, Levy RB, Claro RM, Giovannucci E, et al. The increasing burden of cancer attributable to high body mass index in Brazil. Cancer Epidemiol. 2018;54:63-70. https://doi.org/10.1016/j.canep.2018.03.006

Sun L, Zhu Y, Qian Q, Tang L. Body mass index and prognosis of breast cancer: an analysis by menstruation status when breast cancer diagnosis. Medicine. 2018;97(26):e11220. https://doi.org/10.1097/md.0000000000011220

Sheng JY, Sharma D, Jerome G, Santa-Maria CA. Obese Breast Cancer Patients and Survivors: Management Considerations. Oncology (Williston Park) [Internet]. 2018 [accessed on Nov 7, 2019]. Available from: https://www.cancernetwork.com/breast-cancer/obese-breast-cancer-patients-and-survivors-management-considerations

Sharma AV, Reddin G, Forrestal B, Barac A. Cardiovascular Disease Risk in Survivors of Breast Cancer. Curr Treat Options Cardiovasc Med. 2019;21.https://doi.org/10.1007/s11936-019-0788-2

World Health Organization. Obesity: preventing and managing the global epidemic. WHO Technical Report Series. Genebra: World Health Organization; 1999.

Associação Brasileira para o Estudo da Obesidade e da Síndrome Metabólica (ABESO). VI Diretrizes Brasileiras Obesidade. Brasil: ABESO; 2016.

Dai Y, Wan X, Li X, Jin E, Li X. Neck circumference and future cardiovascular events in a high-risk population - A prospective cohort study. Lipids Health Dis. 2016;15:46. http://dx.doi.org/10.1186/s12944-016-0218-3

Saad MAN, Rosa MLG, Lima GB, Antunes da Cruz Filho R. A circunferência do pescoço prediz a resistência insulínica no idoso? Um estudo transversal na atenção primária no Brasil. Cad Saúde Pública. 2017;33(8):1-8. https://doi.org/10.1590/0102-311x00060916

Lipschitz D. Screening for nutritional status in the elderly. Prim Care. 1994;21(1):55-67.

Ben-Noun L, Laor A. Relationship between changes in neck circumference and cardiovascular risk factors. Exp Clin Cardiol. 2006;11(1):14-20.

Sociedade Brasileira de Cardiologia. 7ª diretriz brasileira de hipertensão arterial. Arq Bras Cardiol. 2016.

Instituto Nacional de Câncer José Alencar Gomes da Silva. ABC do câncer: abordagens básicas para o controle do câncer. 5ª ed. Rio de Janeiro: Instituto Nacional de Câncer José Alencar Gomes da Silva; 2019.

Cunha TRS, Santiago ICA, Motta RST. Nutritional profile and its correlation with the main prognostic factors in women with breast cancer undergoing surgical treatment. Mastology. 2018;28(2):94-101. https://doi.org/10.29289/2594539420180000380

Queiroz SA, Sousa IM, Silva FRM, Lyra CDO, Fayh APT. Nutritional and environmental risk factors for breast cancer: a case-control study. Sci Med. 2018;28(2):1-8. http://dx.doi.org/10.15448/1980-6108.2018.2.28723

Mota JCMG, Martins KA, Mota JF, Freitas-Junior R. Excesso de peso e de gordura androide em mulheres goianas recém-diagnosticadas com câncer de mama. Rev Bras Mastologia. 2016;26(2):50-5. http://dx.doi.org/10.5327/Z201600020004RBM

Souza NHA, Falcão LMN, Nour GFA, Brito J, Castro M, Oliveira M. Breast cancer in young women: an epidemiological study in northeastern Brazil. Sanare. 2017;16(2):60-7.

Cabral ALLV, Giatti L, Casale C, Cherchiglia ML. Social vulnerability and breast cancer: Differentials in the interval between diagnosis and treatment of women with different sociodemographic profiles. Ciên Saúde Coletiva. 2019;24(2):613-22. https://doi.org/10.1590/1413-81232018242.31672016

Instituto Nacional de Câncer José Alencar Gomes da Silva. A situação do câncer de mama no Brasil: síntese de dados dos sistemas de informação. Brasil: Instituto Nacional de Câncer José Alencar Gomes da Silva; 2019.

World Cancer Research Fund, American Institute for Cancer Research. Diet, nutrition, physical activity and breast cancer. Continuous Update Project Expert Report 2018 [Internet]. World Cancer Research Fund; 2018 [acessado em 01 nov. 2019]. Available from: dietandcancerreport.org

Macacu A, Autier P, Boniol M, Boyle P. Active and passive smoking and risk of breast cancer: a meta-analysis. Breast Cancer Res Treat. 2015;154(2):213-24. https://doi.org/10.1007/s10549-015-3628-4

Balekouzou A, Yin P, Pamatika C, Bekolo C, Nambei S, Djeintote M, et al. Reproductive risk factors associated with breast cancer in women in Bangui: a case-control study. BMC Womens Health. 2017;17(1):14. https://doi.org/10.1186/s12905-017-0368-0

Custódio IDD, Marinho EDC, Gontijo CA, Pereira TSS, Paiva CE, De Maia YCP. Impact of chemotherapy on diet and nutritional status of women with breast cancer: A prospective study. PLoS One. 2016;11(6):e0157113. http://dx.doi.org/10.1371/journal.pone.0157113

Boyle T, Vallance JK, Buman MP, Lynch BM. Reallocating time to sleep, sedentary time, or physical activity: associations with waist circumference and body mass index in breast cancer survivors. Cancer Epidemiol Biomarkers Prev. 2017;26(2):254-60. https://dx.doi.org/10.1158%2F1055-9965.EPI-16-0545

Santos EMC, Silva LML, Santos EMC, Souza LS. Associação entre o estado nutricional e a presença de toxicidade gastrointestinal em pacientes com câncer de mama. Braspen J. 2018;33(1):9-14.

Pacholczak R, Klimek-Piotrowska W, Kuszmiersz P. Associations of anthropometric measures on breast cancer risk in pre- and postmenopausal women—a case-control study. J Physiol Anthropol. 2016;35:7. https://dx.doi.org/10.1186%2Fs40101-016-0090-x

Vieira ACR, Sichieri R. Associação do status socioeconômico com obesidade. Physis. 2008;18(3):415-26. http://dx.doi.org/10.1590/S0103-73312008000300003

Ribeiro-Sousa MAS, Mastelaro I, Peria FM, Carrara HA, Andrade JM, Cunha SFC. Weight Gain during Systemic Oncologic Therapy for Breast Cancer: Changes in Food Intake and Physical Activity. Rev Bras Cancerol. 2019;65(2):1-7. https://doi.org/10.32635/2176-9745.RBC.2019v65n2.360

Downloads

Published

2020-04-12

How to Cite

Meneses, T. B., Cunha, T. R. da S., & Burgos, M. G. P. de A. (2020). Nutritional status and cardiovascular risk in women with breast cancer. Mastology, 30, 1–7. Retrieved from https://revistamastology.emnuvens.com.br/revista/article/view/352

Issue

Section

Original Articles