BREAST NECROSIS IN A CHRONIC USER OF WARFARIN

Authors

  • Geraldo Antônio Cassol Prefeitura de Joinville. Mastology Service
  • Fabrício Farias Morales Maternidade Darcy Vargas. Instituto Brasileiro de Controle do Câncer
  • Mariana Luz Stocco Maternidade Darcy Vargas. Instituto Brasileiro de Controle do Câncer
  • Mariana Pimenta Pinheiro Maternidade Darcy Vargas. Instituto Brasileiro de Controle do Câncer

Keywords:

necrosis, breast, warfarin

Abstract

Warfarin-induced skin necrosis is a rare event that generally happens within the first days of warfarin use and is due to the initial, and transitory, prothrombotic state caused by unbalanced pro and anticoagulant factors. We describe the first case of breast necrosis in a 50-year-old woman, who uses warfarin chronically, and had its anticoagulant effect enhanced by the concomitant use of diclofenac.

Downloads

Download data is not yet available.

References

López Valle CA, Hébert G. Warfarin-induced complete bilateral breast necrosis. Br J Plast Surg. 1992;45(8):606-9.

Khalid K. Warfarin-induced necrosis of the breast: case report. J Postgrad Med. 2004;50(4):268-9.

Ejzenberg D, Neusquen LP, Rolnik DL, Lozinsky AC, Piato JR. Breast necrosis induced by the use of coumadin: case report and review of literature. Einstein (Sao Paulo). 2015 Jul-Sep;13(3):417-9.

DeFranzo AJ, Marasco P, Argenta LC. Warfarin-induced necrosis of the skin. Ann Plast Surg. 1995;34(2):203-8.

Au AF, Fosnot J, Wu LC. Coumadin-induced skin necrosis of the breasts: case report. Ann Plast Surg. 2012;69(1):109-10.

Llamas-Velasco M, Alegría V, Santos-Briz Á, Cerroni L, Kutzner H, Requena L. Occlusive Nonvasculitic Vasculopathy. Am J Dermatopathol. 2017 Sep;39(9):637-62.

Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G. Pharmacology and management of the vitamin Kantagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:160S-98S.

Lewandowski K, Zawilska K. Protein C concentrate in the treatment of warfarin-induced skin necrosis in the protein C deficiency. Thromb Haemost. 1994;71:395.

Lane DA, Mannucci PM, Bauer KA, Bertina RM, Bochkov NP, Boulyjenkov V, et al. Inherited thrombophilia: Part 1. Thromb Haemost. 1996;76:651-62.

Karimi K, Odhav A, Kollipara R, Fike J, Stanford C, Hall JC. Acute Cutaneous Necrosis: A Guide to Early Diagnosis and Treatment. J Cutan Med Surg. 2017 Sep/Oct;21(5):425-37.

Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, et al. Dabigatran in the Treatment of Warfarin- Induced Skin Necrosis: A New Hope. Case Rep Dermatol Med. 2016;2016:3121469.

Downloads

Published

2017-10-07

How to Cite

Cassol, G. A., Morales, F. F., Stocco, M. L., & Pinheiro, M. P. (2017). BREAST NECROSIS IN A CHRONIC USER OF WARFARIN. Mastology, 27(4), 359–362. Retrieved from https://revistamastology.emnuvens.com.br/revista/article/view/528

Issue

Section

Case Reports