EPIDEMIOLOGICAL PROFILE OF BREAST CANCER IN A REFERENCE HOSPITAL IN THE NORTH REGION

Authors

  • Francianne Silva Rocha Universidade Federal do Pará
  • Wellington dos Santos Silva Universidade Federal do Pará
  • Eliude Rodrigues do Nascimento Universidade Federal do Pará
  • Alessandra Marques Bacciotti Universidade Federal do Pará

Keywords:

Breast cancer, epidemiological profile, risk factors

Abstract

Introduction: Breast cancer is a public health issue, not only in underdeveloped countries, as is the case of Brazil, but also in developed ones, such as the United States and some Western European countries. The frequency of distribution of different types of cancer varies according to the characteristics of each region, which emphasizes the need to study geographical variations, risk factors, and disease patterns that pervade regional particularities. Objective: The present study describes the epidemiological profile of patients treated at a reference cancer hospital in the North Region of the country and determines the variables of clinical and epidemiological interest related to risk factors for breast cancer. Methods: This is a cross-sectional descriptive study conducted through interviews and analysis of medical records of 114 patients treated at Hospital Ophir Loyola between 2016 and 2017 in the city of Belém, Pará. Data were presented as absolute and relative frequencies. Results: Most women who participated in the study were multiracial, overweight, with a mean age of 51 years, and had low schooling. A little over half of them were born in the inland of the state; the majority lived in the metropolitan area of Belém, 42% in the inland, and only 11% in the countryside. The mean interval between clinical suspicion and diagnostic confirmation was almost 13 months. The most frequent histopathological classification was invasive ductal carcinoma, and the immunohistochemical profile with the higher incidence was luminal B, followed by luminal A. Conclusions: Overweight, considered a risk factor for breast cancer, is modifiable, which underlines the importance of awareness actions for early diagnosis, knowledge of the disease, and encouragement to physical activity and healthy eating habits, in order to reduce morbidity and mortality, and improve the prognosis of women affected by this pathology.

Downloads

Download data is not yet available.

References

Gebrim LH, Quadros LGA. Rastreamento do câncer de mama no Brasil. Rev Bras Ginecol Obstet. 2006;28(6). http://dx.doi.org/10.1590/S0100-72032006000600001

Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Diretrizes Diagnósticas e Terapêuticas do Carcinoma de Mama. Portaria conjunta n° 4 [Internet]. Brasil: Ministério da Saúde; 2018 [acessado em 28 mar. 2018]. Disponível em: http://portalarquivos2.saude.gov.br/images/pdf/2018/fevereiro/07/PORTARIA-no-04-PCDT.carcinoma.mama.2018.pdf

Matos JC, Pelloso SM, Carvalho MDB. Prevalência de fatores de risco para o câncer de mama no município de Maringá, Paraná. Rev Latino-Am Enfermagem [Internet]. 2010 [acessado em 20 mar. 2018];18(3). Disponível em: http://rlae.eerp.usp.br/. DOI: http://dx.doi.org/10.1590/S0104-11692010000300009

Pinho VFS, Coutinho ESF. Variáveis associadas ao câncer de mama em usuárias de unidades básicas de saúde. Cad

Saúde Pública [Internet]. 2007 [20 mar. 2018];23(5):1061-69. Disponível em: http://www.scielo.br/scielo.php?pid=s0102-311x2007000500008&script=sci_abstract&tlng=pt. http://dx.doi.org/10.1590/S0102-311X2007000500008

Jung W, Kieling EF, Kunzler IM, Lazzari DD, Nascimento ERP, Alves DLF. Fatores de risco para câncer de mama no setor calçadista. Rev Baiana Enfermagem [Internet]. 2014 [acessado em 20 mar. 2018];28(2):145-55. Disponível em: https://portalseer.ufba.br/index.php/enfermagem/article/view/10083/8866

Lloga TG, Iglesia YF, Garbey MN, Bornot YI, Ordúñez DF. Incidencia de cáncer de mama en mujeres de la provincia Guantánamo en el período 2015-2016. Rev Inf Cientifica [Internet]. 2017 [acessado em 20 mar. 2018];96(5):866-74. Disponível em: http://www.medigraphic.com/pdfs/revinfcie/ric-2017/ric175h.pdf

Brasil. Ministério da Saúde. Instituto Nacional de Câncer José Alencar Gomes da Silva. Estimativa | 2016 Incidência de Câncer no Brasil [Internet]. Rio de Janeiro: Instituto Nacional de Câncer José Alencar Gomes da Silva; 2015 [acessado em 20 mar. 2018]. Disponível em: http://www.inca.gov.br/bvscontrolecancer/publicacoes/edicao/Estimativa_2016.pdf

Batiston AP, Tamaki EM, Souza LA, Santos MLM. Conhecimento e prática sobre os fatores de risco para o câncer de mama entre mulheres de 40 a 69 anos. Rev Bras Saúde Matern Infant [Internet]. 2011 [acessado em 20 mar. 2018];11(2):163-71. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292011000200007]. http://dx.doi.org/10.1590/S1519-38292011000200007

Papa AM, Pirfo CBL, Murad AM, Ribeiro GMQ, Fagundes TC. Impacto da obesidade no prognóstico do câncer de mama. Rev Bras Oncol Clín [Internet]. 2013 [acessado em 21 mar. 2018];9(31):25-30. Disponível em https://www.sboc.org.br/sboc-site/revista-sboc/pdfs/31/artigo3.pdf

Picon‐Ruiz M, Morata-Tarifa C, Valle-Goffin JJ, Friedman ER, Slingerland JM. Obesity and adverse breast cancer risk and outcome: mechanistic insights and strategies for intervention. CA Cancer J Clin [Internet]. 2017 [acessado em 21 mar. 2018];67(5):378-

Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591063/. http://doi.org/10.3322/caac.21405

Neuhouser ML, Aragaki AK, Prentice RL, Manson JE, Chiebowski R, Carty CL, et al. Overweight, Obesity and Postmenopausal Invasive Breast Cancer Risk. JAMA Oncol [Internet]. 2015 [acessado em 21 mar. 2018];1(5):611-21. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070941. https://dx.doi.org/10.1001%2Fjamaoncol.2015.1546

Daling JR, Malone KE, Doody DR, Johnson LG, Gralow JR, Porter PL. Relation of body mass index to tumor markers

and survival among young women with invasive ductal breast carcinoma. Cancer [Internet]. 2001 [acessado em 21 mar. 2018];92(4):720-9. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/11550140

Sedó KS, Lima CA, Carneiro PCPD, Albuquerque LS, Araújo CO, Castro AS, et al. Conhecimento nutricional de mulheres com câncer de mama e sua relação com o estado nutricional. Rev Bras Promoç Saúde [Internet]. 2013 [acessado em 21 mar. 2018];26(1):71-8. Disponível em: http://periodicos.unifor.br/RBPS/article/view/2626/pdf_1

Reis FP, Santos MEG, Sena WR, Santana R, Freitas TS, Silveira HF, et al. Perfil epidemiológico das pacientes com câncer de mama atendidas em uma unidade de saúde em São Francisco do Conde, Ba. Rev Ciências Médicas Biológicas [Internet]. 2016 [acessado em 21 mar. 2018];15(2):144-50. Disponível em: https://portalseer.ufba.br/index.php/cmbio/article/view/1519. http://dx.doi.org/10.9771/cmbio.v15i2.15194

National Cancer Institute. Breast Cancer Risk in American Women [Internet]. Bethesda: National Cancer Institute; 2012 [acessado em 23 mar. 2018]. Disponível em: https://www.cancer.gov/types/breast/risk-fact-sheet

Sousa MM, Figueredo SB, Fernandes RM. Perfil clínicoepidemiológico de mulheres com neoplasia de mama atendidas no hospital regional de referência no município de Araguaína-TO no período de 2000 a 2015. Rev Interdisciplinar da Universidade Federal do Tocantins [Internet]. 2016 [acessado

mar. 2018];2(2):283-306. Disponível em: https://sistemas.uft.edu.br/periodicos/index.php/desafios/article/view/2124/8738. http://dx.doi.org/10.20873/uft.2359-3652.2016v2n2p283

Russo J, Russo IH. Toward a physiological approach to breast cancer prevention. Cancer Epidemiol Biomarkers Prev [Internet]. 1994 [acessado em 27 mar. 2018];3(4):353‑64. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/8061586

Ursin G, Bernstein L, Lord SJ, Karim R, Deapen D, Press MF, et al. Reproductive Factors and Subtypes of Breast Cancer Defined by Hormone Receptor and Histology. Brit J Cancer [Internet]. 2005 [acessado em 27 mar. 2018];93(3):364-71. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361558. https://dx.doi.org/10.1038%2Fsj.bjc.6602712

Dugno MLG, Soldatelli JS, Daltoé T, Rosado JO, Spada P, Formolo F. Perfil do câncer de mama e relação entre fatores de risco e estadiamento clínico em hospital do Sul do Brasil. Rev Bras Oncol Clin [Internet]. 2013 [acessado em 27 mar. 2018];60‑6. Disponível em: https://www.sboc.org.br/sboc-site/revista-sboc/pdfs/36/artigo3.pdf

Peres VC, Veloso DLC, Xavier RM, Salge AKM, Guimarães JV. Câncer de mama em mulheres: recidiva e sobrevida em cinco anos. Texto Contexto Enferm [Internet]. 2015 [acessado em 28 mar. 2018];24(3):740-47. Disponível em: http://www.scielo.br/pdf/tce/v24n3/pt_0104-0707-tce-24-03-00740.pdf. http://dx.doi.org/10.1590/0104-07072015000600014

Downloads

Published

2018-07-17

How to Cite

Rocha, F. S., Silva, W. dos S., Nascimento, E. R. do, & Bacciotti, A. M. (2018). EPIDEMIOLOGICAL PROFILE OF BREAST CANCER IN A REFERENCE HOSPITAL IN THE NORTH REGION. Mastology, 28(3), 169–175. Retrieved from https://revistamastology.emnuvens.com.br/revista/article/view/559

Issue

Section

Original Articles