TRANSFORMATION OF FIBROADENOMA TO PHYLLODES TUMOR AND THE USE OF ONCOPLASTIC TECHNIQUE FOR BREAST CONSERVATIVE TREATMENT
Keywords:
phyllodes tumor, diagnostic, fibroadenoma, oncoplastic technique, breast conservative surgeryAbstract
Phyllodes tumors (PT) are rare neoplasms accounting for <1% of breast lesions. A transformation of a fibroadenoma (FA) to a PT is even more rare and unpredictable. Many challenges face PT management, since diagnostic through surgical treatment. We describe a case of a 63-year old woman with PT that was previously diagnosed as a FA who underwent an oncoplastic conservative surgery. A review of the literature on the diagnostic and surgical management of PT was performed. The diagnostic of PT can be hard mostly in needle biopsy, and the close follow up of negative lesions is recommended. Oncoplastic techniques might be an important tool on the conservative treatment of these patients.
Downloads
References
Sanders LM, Sara R. The growing fibroadenoma. Acta Radiologica Open. 2015;4(4):1-5. http://doi.org/10.1177/2047981615572273
Sanders LM, Daigle ME, Tortora M, Panasiti R. Transformation of benign fibroadenoma to malignant phyllodes tumor. 2015;4(4):1-3. http://doi.org/10.1177/2058460115592061
Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, et al. Phyllodes tumors of the breast: a consensus review. Histopathology. 2016;68(1):5-21. http://doi.org/10.1111/his.12876
Krings G, Bean GR, Chen YY. Fibroepithelial lesions; The WHO spectrum. Semin Diagn Pathol. 2017;34(5):438-52. http://doi.org/10.1053/j.semdp.2017.05.006.
Boff RA. Compendio de mastologia: abordagem multidisciplinar. Cap. 28. In: RA Boff, De Carli AC, Brenelli H, Brenelli FP, De Carli LS, Sauer FZ, et al. Editors. Compendio de mastologia: abordagem multidisciplinar. 1st ed. Caxias do Sul: I C DE SOUZA OLIVEIRA LIVRARIA ME, 2015. p.331-6.
Lawton TJ, Acs G, Argani P, Farshid G, Gilcrease M, Goldstein N, et al. Interobserver variability by pathologists in the distinction between cellular fibroadenomas and phyllodes tumors. Int J Surg Pathol. 2014;22(8):695-8. http://doi.org/10.1177/1066896914548763
Choi J, Koo JS. Comparative study of histological features between core needle biopsy and surgical excision in phyllodes tumor. Pathol Int. 2012;62(2):120-6. http://doi.org/10.1111/j.1440-1827.2011.02761.x
Abe M, Miyata S, Nishimura S, Iijima K, Makita M, Akiyama F, et al. Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors. Breast Cancer. 2011;18(4):268‑72. http://doi.org/10.1007/s12282-009-0185-x
Mangi AA, Smith BL, Gadd MA, Tanabe KK, Ott MJ, Souba WW, et al. Surgical management of phyllodes tumors. Arch Surg. 1999;134(5):487-93. http://doi.org/10.1001/archsurg.134.5.487
J Onkendi EO, Jimenez RE, Spears GM, Harmsen WS, Ballman KV, Hieken TJ. Surgical treatment of borderline and malignant phyllodes tumors: the effect of the extent of resection and tumor characteristics on patient outcome. Ann Surg Oncol. 2014 Oct;21(10):3304-9. http://doi.org/10.1245/s10434-014-3909-x
Reinfuss M, Mituś J, Duda K, Stelmach A, Ryś J, Smolak K. The Treatment and Prognosis of Patients with Phyllodes Tumor of the Breast. Cancer. 1996;77(5):910-6.
Cochrane RA, Valasiadou P, Wilson AR, Al-Ghazal SK, Macmillan RD. Cosmesis and satisfaction after breast‑conserving surgery correlates with the percentage of breast volume excised. Br J Surg. 2003;90(12):1505-9.
Clough KB, Lewis JS, Couturaud B, Fitoussi A, Nos C, Falcou MC. Oncoplastic techniques allow extensive resections for breast-conserving therapy of breast carcinomas. Ann Surg. 2003;237(1):26-34.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Julia Dias do Prado, Roberto José da Silva Vieira, Waldyr Gomes da Costa Neto, Linda Lorena Gonzalez de Castro, Bruno Bohrer Flores, Lea Pikelhaizen Velloso
This work is licensed under a Creative Commons Attribution 4.0 International License.