Complex fibroadenoma
bibliometric literature review and presentation of a clinical case
Keywords:
diagnosis, fibroadenoma, therapeuticsAbstract
Fibroadenomas (FAs) are benign fibro-epithelial tumours of the breast characterized by being biphasic and having stromal and epithelial components. It is estimated that FAs affect more than 20 percent of the general population aged 16–40 years old. Complex FAs are a sub-type of fibroadenoma presenting one or more pathological characteristics, such as epithelial calcifications, apocrine metaplasias, sclerosing adenoma and cysts larger than 3 mm. According to studies elsewhere, women with complex FAs are 3.1 times more likely to develop breast cancer. The objective of the present study was to map the scientific production of articles on complex FA in the international literature. The ISI Web of Knowledge (Web of Science), one of the main scientific databases in the world, was searched with the following terms: (“complex” and “fibroadenoma”) or (“fibroadenoma” and “complex”). Only articles published between 1981 and 2019 were considered for a bibliometric review, in which 160 articles from 126 different periodicals were identified after using refinement filters. Moreover, a clinical case was also discussed based on the patient’s medical record and interview.
Downloads
References
Dupont WD, Page DL, Parl FF, Vnencak-Jones CL, Plummer Jr. WD, Rados MS, et al. Long-term risk of breast cancer in women with fibroadenoma. New Engl J Med [Internet]. 1994 [accessed on Sept. 13, 2019];331(1):10-5. Available at: https://www.ncbi.nlm.nih.gov/pubmed/8202095 https://doi.org/10.1056/nejm199407073310103
Kuijper A, Mommers EC, van der Wall E, van Diest PJ. Histopathology of fibroadenoma of the breast. Am J Clin Pathol [Internet]. 2001 [accessed on Sept. 2, 2019];115(5):736-42. Available at: https://www.ncbi.nlm.nih.gov/pubmed/11345838 https://doi.org/10.1309/f523-fmjv-w886-3j387
Pinto J, Aguiar AT, Duarte H, Vilaverde F, Rodrigues A, Krug JL. Simple and Complex Fibroadenomas. Are There Any Distinguishing Sonographic Features? J Ultrasound Med [Internet]. 2014 [accessed on Sept. 13, 2019];33(3):415-9. Available at: https://www.ncbi.nlm.nih.gov/pubmed/24567452 https://doi.org/10.7863/ultra.33.3.415
Ohashi R, Matsubara M, Watarai Y, Yanagihara K, Yamashita K, Tsuchiya S-I, et al. Cytological features of complex type fibroadenoma in comparison with non-complex type fibroadenoma. Breast Cancer [Internet]. 2016 [accessed on Sept. 2, 2019];23(5):724-31. Available at: https://www.ncbi.nlm.nih.gov/pubmed/26249102 https://doi.org/10.1007/s12282-015-0632-9
Almeida ACO. Fibroadenomas Mamários – que entidade?: artigo de revisão [dissertation] [Internet]. Coimbra: Faculdade de Medicina, Universidade de Coimbra; 2015 [accessed on Sept. 17, 2019]. Available at: https://estudogeral.uc.pt/bitstream/10316/31286/1/Trabalho%20final%206%C2%BAano_%20Fibroadenomas%20Mam%C3%A1rios.pdf
Sklair-Levy M, Sella T, Alweiss T, Craciun I, Libson E, Mally B. Incidence and Management of Complex Fibroadenomas. Am J Roentgenol [Internet]. 2008 [accessed on Sept. 11, 2019];190(1):214-8. Available at: https://www.ncbi.nlm.nih.gov/pubmed/18094314 https://doi.org/10.2214/ajr.07.2330
Nazário ACP, Rego MF, Oliveira VM. Nódulos benignos da mama: uma revisão dos diagnósticos diferenciais e conduta. Rev Bras GinecolObstet[Internet]; 2007[accessedonSept. 17,2019];29(4):211-9. Available at: http://www.scielo.br/scielo.php?pid=S0100-72032007000400008&script=sci_abstract&tlng=pt https://doi.org/10.1590/S0100-72032007000400008
Pao ML. Concepts of information retrieval. Englewood: Libraries Unlimited; 1989. 285 p.
Lim WK, Ong CK, Tan J, Thike AA, Ng CC, Rajasegaran V, et al. Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma. Nat Genet. 2014;46(8):877-80. https://doi.org/10.1038/ng.3037
Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, et al. Phyllodes tumours of the breast: a consensus review. Histopathology. 2016;68(1):5-21. https://dx.doi.org/10.1111%2Fhis.12876
Delfino RJ, Smith C, West JG, Lin HJ, White E, Liao SY, et al. Breast cancer, passive and active cigarette smoking and N-acetyltransferase 2 genotype. Pharmacogenetics. 2000;10(5):461-9. https://doi.org/10.1097/00008571-200007000-00009
Delfino RJ, Sinha R, Smith C, West J, White E, Lin HJ, et al. Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype. Carcinogenesis. 2000;21(4):607-15. https://doi.org/10.1093/carcin/21.4.607
El-Wakeel H, Umpleby HC. Systematic review of fibroadenoma as a risk factor for breast cancer. Breast. 2003;12(5):302-7. https://doi.org/10.1016/s0960-9776(03)00123-1
Kabat GC, Jones JG, Olson N, Negassa A, Duggan C, Ginsberg M, et al. A multi-center prospective cohort study of benign breast disease and risk of subsequent breast cancer. Cancer Causes Control. 2010;21(6):821-8. https://doi.org/10.1007/s10552-010-9508-7
Yoshida M, Sekine S, Ogawa R, Yoshida H, Maeshima A, Kanai Y, et al. Frequent MED12 mutations in phyllodes tumours of the breast. Br J Cancer. 2015;112:1703-8. https://doi.org/10.1038/bjc.2015.116
Sawhney N, Garrahan N, Douglas-Jones AG, Williams ED. Epithelial--stromal interactions in tumors. A morphologic study of fibroepithelial tumors of the breast. Cancer. 1992;70(8):2115-20. https://doi.org/10.1002/1097-0142(19921015)70:8<2115::aid-cncr2820700818>3.0.co;2-k
Gordon PB, Gagnon FA, Lanzkowsky L. Solid Breast Masses Diagnosed as Fibroadenoma at Fine-Needle Aspiration Biopsy: Acceptable Rates of Growth at Long-term Follow-up. Radiology [Internet]. 2003 [accessed on Sept. 15, 2019];229(1):233-8. Available at: https://www.ncbi.nlm.nih.gov/pubmed/14519878 https://doi.org/10.1148/radiol.2291010282
Derossi DR, Ito K, Couto Filho JO, Bacchi CE. Avaliação da expressão da proteína bcl-2 no carcinoma de mama: estudo em punção aspirativa por agulha fina; correlação com grau histológico em espécimes cirúrgicos correspondentes. J Bras Patol Med Lab [Internet]. 2003 [accessed on Sept. 11, 2019];39(3):229-35. Available at: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442003000300010 https://doi.org/10.1590/S1676-24442003000300010
Darooei M, Khan F, Rehan M, Zubeda S, Jeyashanker E, Annapurna S, et al. Med12 somatic mutations encompassing exon 2 associated with benign breast fibroadenomas and not breast carcinoma in Indian women. J Cell Biochem [Internet]. 2018 [accessed on Mar. 3, 2019];120(1):182-91. Available at: https://doi.org/10.1002/jcb.27293
Stachs A, Stubert J, Reimer T, Hartmann S. Benign Breast Disease in Women. Dtsch Arztebl Int [Internet]. 2019 [accessed on Mar. 5, 2019];116(33-34):565-74. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794703/ https://doi.org/10.3238%2Farztebl.2019.0565
Roveda Junior D, Piatto S, Oliveira VM, Rinaldi JF, Ferreira CAP, Fleury ECF. Valores preditivos das categorias 3, 4 e 5 do Sistema DI-RADS em lesões mamárias noduláveis não-palpáveis avaliadas por mamografia, ultra-sonografia e ressonância magnética. Radiol Bras [Internet]. 2007 [accessed on Mar. 3, 2019];40(2):93-8. Available at: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842007000200006 https://doi.org/10.1590/S0100-39842007000200006
Calado SS, Lima MCCA. Estudo morfológico dos fibroadenomas da mama: uma análise comparativa entre grupos etários. J Bras Patol Med Lab [Internet]. 2004 [accessed on Sept. 11, 2019];40(6):411- 9. Available at: http://www.scielo.br/scielo.php?pid=S1676-24442004000600009&script=sci_abstract&tlng=pt https://doi.org/10.1590/S1676-24442004000600009
Fleury EFC, Rinaldi JF, Piato S, Fleury JCV, Roveda Junior D. Appearance of breast masses on sonoelastography with special focus on the diagnosis of fibroadenomas. Eur Radiol [Internet]. 2009 [accessed on Sept. 11, 2019];19(6):1337-46. Available at: https://www.ncbi.nlm.nih.gov/pubmed/19159934 https://doi.org/10.1007/s00330-008-1285-2
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Ana Beatriz Aguiar Cardoso, Gabriele Cristina Schröder, Polyanna Zimermann, Thiago Santos Lima Almendra, Antonione Santos Bezerra Pinto
This work is licensed under a Creative Commons Attribution 4.0 International License.