Prognosis of age factor in breast cancer

Abstract

This study was like objective compare the results of a group of women with breast cancer at the age under 40 years to another group outside this age range. It is an observational retrospective cohort with data collection in electronic medical record system of 575 cases in the period from February 2001 to July 2013. The exposure factor was age at diagnosis, dividing the sample into two groups: those aged up to 40 years and the age above 40 years. The data were collected: name, age, origin, tumor type, tumor grade, tumor size, pathological stage, type of treatment, sentinel node, survival at 5 and 10 years. Inclusion in the study was allowed to the case with all the data mentioned above. We excluded patients with ductal carcinoma in situ – Stage 0 and Stage 4, being treated randomly staging upon survival analysis. Adopting the criteria of inclusion and exclusion, the study sample consisted of 331 women, arranged in two groups: Group 1 with 30 cases (aged under 40 years) and Group 2 included 301 patients (age 40 or older). The study shows a different profile of the disease in women under 40 with significance set at p <0.05 in Staging and having shorter survival after pairing Staging in 5 years. Did not reach significance in tumor size, grade, histology, type of treatment, results of sentinel lymph node and possibly survival of 10 years the number of cases.