Breast cancer in men
Keywords:
Breast cancer, Male, Drug therapy, RadiotherapyAbstract
Breast cancer in men is a little known disease. His approach in clinical trials and publications is uncommon. A literature review was conducted, focusing on the epidemiology, risk factors, pathology and tumor markers of this disease. Corresponds to 1% of all breast cancers. Risk factors include hiperestrogenism, age, Jewish ancestry, family history and Klinefelter syndrome. About 90% of tumors are invasive ductal. Exhibit estrogen and progesterone receptor positive in 80 to 90% of cases. Treatment is similar to breast cancer in women: surgery, hormone therapy, chemotherapy and radiotherapy are used, following the women’s guidelines. Prognostic factors include tumor size, histological grade and lymph node involvement. Breast cancer is similar in men and women; however, male cases had immunohistochemical features, but there aren’t sufficient data to evaluate the impact of this feature on the prognosis and treatment of this malignancy studies.
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