Breast mass as first clinical manifestation of metastatic liposarcoma myxoid

case report

Abstract

The authors describe a female’s patient case report who presented, as first clinical presentation of metastatic myxoid liposarcoma, the presence of breast mass. We describe a case report of a 37 years old female patient who presented, as unique clinical manifestation, a right breast mass of 3.8 cm, palpable, fibroelastic, mobile and painless. The screening exams (breast ultrasound, mammograms, fine needle aspiration) revealed a benign breast mass (birads 2) and we performed a lumpectomy required by the patient. As medical records, the patient presented a surgical treatment for intramuscular left thigh’s myxoid liposarcoma, histologic grade 2 – pT2pNx – plus local radiation. The final pathology analysis, after surgery, revealed that the breast mass was a metastatic myxoid liposarcoma, 3,8 cm of diameter, mitotic index 4/10 with immunohistochemical profile (CK AE!/AE3, S100 protein, estrogen and progesterone receptors and Ki 67) compatible with this diagnosis. With these findings, we made a complete screening (abdomen, thorax and CNS CT-scan, bone scintigraphy) that revealed extensive metastatic disease. The mammary glands can be primary site of various metastatic diseases, so we describe the occurrence of breast mass as first manifestation of metastatic thigh’s myxoid liposarcoma.