Prolonged response for 43 cycles of trastuzumab entansine (T‑DM1) in a patient with metastatic breast cancer with HER2 overexpression

case report

Authors

  • Larissa Andressa Orsolini Hospital Araújo Jorge
  • Luiz Fernando Jubé Ribeiro Hospital Araújo Jorge
  • Ruff Freitas Junior Hospital Araújo Jorge
  • Geraldo Silva Queiroz Hospital Araújo Jorge
  • Tâmara Naves Moraes Hospital Araújo Jorge

Keywords:

Neoplasms, Breast, Neoplasm metastasis, Drug therapy, Antibodies monoclonal

Abstract

The objective of this study was to report a case of a patient with metastatic breast cancer overexpressing HER2 that was randomized to receive trastuzumab entansine (T‑DM1), while participating in a randomized phase III clinical trial, who has showed complete response of the target lesions. The data were obtained through review of medical records, interview with the patient and review of the study questionnaires. This case report is justified due to the very long clinical response to the T-DM1 and also to the safe profile of this novel anti-HER agent.

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Author Biographies

Larissa Andressa Orsolini, Hospital Araújo Jorge

Setor de Pesquisa Clínica do Serviço de Ginecologia e Mama da ACCG‑HAJ – Goiânia (GO), Brasil.

Luiz Fernando Jubé Ribeiro, Hospital Araújo Jorge

Setor de Pesquisa Clínica do Serviço de Ginecologia e Mama da ACCG‑HAJ – Goiânia (GO), Brasil.

Ruff Freitas Junior, Hospital Araújo Jorge

Setor de Pesquisa Clínica do Serviço de Ginecologia e Mama da ACCG‑HAJ – Goiânia (GO), Brasil.

Geraldo Silva Queiroz, Hospital Araújo Jorge

Setor de Pesquisa Clínica do Serviço de Ginecologia e Mama da ACCG‑HAJ – Goiânia (GO), Brasil.

Tâmara Naves Moraes, Hospital Araújo Jorge

Setor de Pesquisa Clínica do Serviço de Ginecologia e Mama da ACCG‑HAJ – Goiânia (GO), Brasil.

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Published

2016-01-20

How to Cite

Orsolini, L. A., Ribeiro, L. F. J., Freitas Junior, R., Queiroz, G. S., & Moraes, T. N. (2016). Prolonged response for 43 cycles of trastuzumab entansine (T‑DM1) in a patient with metastatic breast cancer with HER2 overexpression: case report. Revista Brasileira De Mastologia, 26(1), 31–36. Retrieved from https://revistamastology.emnuvens.com.br/rbm/article/view/206

Issue

Vol. 26 No. 1 (2016)

Section

Case Report

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.