Metaplastic breast carcinoma with osteosarcomatoid differentiation

a case report

Abstract

This is a case report of an osteosarcomatoid metaplastic breast carcinoma in a hospital in Teresina, Brazil, with review and discussion on the theme. Breast metaplastic carcinoma is more common in women aged 55 and 60 years old. It is usually in the form of a palpable mass with no predilection for any quadrant and rapid growth and is generally larger than other types of breast tumors. These tumors have few receptors for sex hormones. In the case of metaplastic carcinoma with osteosarcomatoid differentiation, its presentation is quite aggres- sive. A decision on the treatment procedure presents difficulties due to the low number of cases reported in the literature. In this report, we present a patient with metaplastic carcinoma and sarcomatoid differentiation in the right upper quadrant of the right breast. It was performed a mastectomy with quadrant skin resection and segment of the pectoral muscle infiltration by the tumor with preservation of the rest of the skin and papiloareolar complex. It will be discussed the pathological findings. Due to the several treatment options available to the patient, it can be concluded that more studies must be done on what kind of treatment has the greatest impact on patient prognosis, as well as the role of radiotherapy/chemotherapy on patient.