Metaplastic breast carcinoma metastatic to the lung, liver and bone

case report and literature review

Authors

  • Sahâmia Martins Ribeiro Universidade Federal do Piauí
  • Josana de Moraes Coelho Universidade Federal do Piauí
  • Rafael Bandeira Lages Universidade Federal de São Paulo
  • Edson Santos Ferreira Filho Universidade Federal do Piauí
  • Aline Reis Ferro Clínica Oncomédica
  • Sabas Carlos Vieira Universidade Federal do Piauí

Keywords:

Carcinoma, Breast, Metaplasia, Neoplasm metastasis

Abstract

Metaplastic carcinoma is uncommon and represents less than 5% of breast carcinomas have been reported. This type is a tumor characterized by a heterogeneous mixture of adenocarcinoma with other histological elements as squamous cell, spindle or another mesenchymal differentiation. We present a case of metaplastic breast carcinoma in an 63 year-old patient. An ultrasound (US) of the left breast revealed solid, heterogeneous lesion occupying the upper quadrants and the retroareolar region, measuring 15.1x8.6 cm. Ultrasonography of the left axilla showed ovoid homogeneous solid nodule with a diameter of 2.4x1.9 cm. The patient underwent modified radical mastectomy with axillary lymphadenectomy. The immunohistochemical analysis showed the diagnosis of invasive metaplastic carcinoma with squamous component and spindle cells. There was presence of distant metastasis to lungs, liver, left anterior rib. Currently, the patient is being treated with palliative chemotherapy of six cycles of 5-fluorouracil, epirubicin and cyclophosphamide.

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Author Biographies

Sahâmia Martins Ribeiro, Universidade Federal do Piauí

Estudante de graduação em Medicina pel Universidade Federal do Piauí (UFPI) – Teresina (PI), Brasil.

Josana de Moraes Coelho, Universidade Federal do Piauí

Estudante de graduação em Medicina pela Universidade Federal do Piauí (UFPI) – Teresina (PI), Brasil.

Rafael Bandeira Lages, Universidade Federal de São Paulo

Residente em Clínica Médica pela Universidade Federal de São Paulo (UNIFESP) – São Paulo (SP); graduação em Medicina pela UFPI – Teresina (PI), Brasil

Edson Santos Ferreira Filho, Universidade Federal do Piauí

Médico graduado em Medicina pela UFPI – Teresina (PI), Brasil.

Aline Reis Ferro, Clínica Oncomédica

Médica Patologista da Oncomédica – Teresina (PI), Brasil.

Sabas Carlos Vieira, Universidade Federal do Piauí

Médico Cirurgião Oncológico; Professor assistente da UFPI – Teresina (PI), Brasil.

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Published

2012-04-29

How to Cite

Ribeiro, S. M., Coelho, J. de M., Lages, R. B., Ferreira Filho, E. S., Ferro, A. R., & Vieira, S. C. (2012). Metaplastic breast carcinoma metastatic to the lung, liver and bone: case report and literature review. Revista Brasileira De Mastologia, 22(2), 70–74. Retrieved from https://revistamastology.emnuvens.com.br/rbm/article/view/61

Issue

Vol. 22 No. 2 (2012)

Section

Case Report

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.