Malignant phyllodes tumor of the breast with lymph node metastasis: a case report
DOI:
https://doi.org/10.29289/2594539420230008Keywords:
malignant phyllodes tumor, lymphatic metastasis, modified radical mastectomyAbstract
In the present case report we aim to describe a rare case of malignant phyllodes tumor in a young patient who presented with a fast-growing mass in the right breast, with an enlargement in the axillary lymph node ipsilateral to the lesion. Perioperative histopathological analysis confirmed malignancy in two out of five excised lymph nodes. Modified radical mastectomy was performed in the right breast, with axillary dissection levels I and II. One month after the first consultation, surgical margins were increased. The patient underwent adjuvant chemotherapy as a complement to surgical treatment. She had tumor recurrence 56 days after surgical treatment. The patient passed away six months after diagnosis.
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1. Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, et al. Phyllodes tumours of the breast: a consensus review. Histopathology. 2016;68(1):5-21. https://doi.org/10.1111/his.12876
2. Zhou ZR, Wang CC, Yang ZZ, Yu XL, Guo XM. Phyllodes tumors of the breast: diagnosis, treatment and prognostic factors related to recurrence. J Thorac Dis. 2016;8(11):3361-8. https://doi.org/10.21037/jtd.2016.11.03
3. Limaiem F, Kashyap S. Phyllodes tumor of the breast. In: StatPearls. Treasure Island: StatPearls Publishing; 2022.
4. Zhang Y, Kleer CG. Phyllodes tumor of the breast: histopathologic features, differential diagnosis, and molecular/genetic updates. Arch Pathol Lab Med. 2016;140(7):665-71. https://doi.org/10.5858/arpa.2016-0042-RA
5. Pantoja Garrido M, Frías Sánchez Z, Albalat Fernández R, Gutiérrez Domingo A. Tumor Phyllodes maligno gigante de mama; neoplasia infrecuente de mal pronóstico. A propósito de un caso clínico. Rev Chil Obstet Ginecol. 2017;82(3):330-7. https://doi.org/10.4067/s0717-75262017000300330
6. Schillebeeckx C, Verbeeck G, Daenen G, Servaes D, Bronckaers M. A giant phyllodes tumor of the breast. Rare Tumors. 2016;8(3):6299. https://doi.org/10.4081/rt.2016.6299
7. Hauser H, Hammer R, Schöllnast H, Humer-Fuchs U, Kriegl D, Fuchsjäger M, et al. Malignant phyllodes tumor of the breast with axillary lymph node metastasis: case report and review of the literature. Eur Surg. 2022;54:156-62. https://doi.org/10.1007/s10353-022-00760-0
8. Korula A, Varghese J, Thomas M, Vyas F, Korula A. Malignant phyllodes tumour with intraductal and invasive carcinoma and lymph node metastasis. Singapore Med J. 2008;49(11):e318-21. PMID: 19037540.
9. Parfitt JR, Armstrong C, O'malley F, Ross J, Tuck AB. In-situ and invasive carcinoma within a phyllodes tumor associated with lymph node metastases. World J Surg Oncol. 2004;2:46. https://doi.org/10.1186/1477-7819-2-46
10. Shafi AA, AlHarthi B, Riaz MM, AlBagir A. Gaint phyllodes tumour with axillary & interpectoral lymph node metastasis; a rare presentation. Int J Surg Case Rep. 2020;66:350-5. https://doi.org/10.1016/j.ijscr.2019.12.026
11. Testori A, Meroni S, Errico V, Travaglini R, Voulaz E, Alloisio M. Huge malignant phyllodes breast tumor: a real entity in a new era of early breast cancer. World J Surg Oncol. 2015;13:81. https://doi.org/10.1186/s12957-015-0508-7
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Copyright (c) 2025 Guilherme Vicentini, José Clemente Linhares, Gabriela Borsari, Heloisa Zandoná Linhares
This work is licensed under a Creative Commons Attribution 4.0 International License.
