RADIOTHERAPY IN BREAST DUCTAL CARCINOMA IN SITU

Authors

  • Gustavo Nader Marta Universidade de São Paulo
  • Heloísa de Andrade Carvalho Hospital Sírio-Libanês

Keywords:

Breast, ductal carcinoma in situ, radiotherapy

Abstract

Breast ductal carcinoma in situ (DCIS) comprises a heterogeneous group of lesions with different forms of clinical and pathological presentation. Postoperative radiotherapy is usually performed in DCIS patients who underwent conservative breast surgery. The objective of the present study was to describe indications and clinical evidences of radiotherapy for breast DCIS patients.

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Author Biographies

Gustavo Nader Marta, Universidade de São Paulo

Hospital Sírio-Libanês, Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, Faculdade de Medicina da Universidade de São Paulo

Heloísa de Andrade Carvalho, Hospital Sírio-Libanês

Hospital Sírio-Libanês, Faculdade de Medicina da Universidade de São Paulo

References

Allred DC. Ductal carcinoma in situ: terminology, classification, and natural history. J Natl Cancer Inst Monogr. 2010;2010:134-8. https://doi.org/10.1093/jncimonographs/lgq035

Rosner D, Bedwani RN, Vana J, Baker HW, Murphy GP. Noninvasive breast carcinoma: results of a national survey by the American College of Surgeons. Ann Surg. 1980;192:139-47.

Solin LJ, Fourquet A, Vicini FA, Taylor M, Olivotto IA, Haffty B, et al. Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast. Cancer. 2005;103:1137-46. https://doi.org/10.1002/cncr.20886

Cutuli B, Cohen-Solal-le Nir C, de Lafontan B, Mignotte H, Fichet V, Fay R, et al. Breast-conserving therapy for ductal carcinoma in situ of the breast: the French Cancer Centers’ experience. Int J Radiat Oncol Biol Phys. 2002;53:868-79.

Fisher B, Land S, Mamounas E, Dignam J, Fisher ER, Wolmark N. Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience. Semin Oncol. 2001;28:400-18.

Wapnir IL, Dignam JJ, Fisher B, Mamounas EP, Anderson SJ, Julian TB, et al. Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS. J Natl Cancer Inst. 2011;103:478-88. https://doi.org/10.1093/jnci/djr027

Bijker N, Peterse JL, Duchateau L, Julien JP, Fentiman IS, Duval C, et al. Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma-in-situ: analysis of European Organization for Research and Treatment of Cancer Trial 10853. J Clin Oncol. 2001;19:2263-71. https://doi.org/10.1200/JCO.2001.19.8.2263

Donker M, Litière S, Werutsky G, Julien JP, Fentiman IS, Agresti R, et al. Breast-conserving treatment with or without radiotherapy in ductal carcinoma In Situ: 15-year recurrence rates and outcome after a recurrence, from the EORTC 10853 randomized phase III trial. J Clin Oncol. 2013;31:4054-9. https://doi.org/10.1200/JCO.2013.49.5077

Houghton J, George WD, Cuzick J, Duggan C, Fentiman IS, Spittle M, et al. Radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial. Lancet. 2003;362:95-102. REFEReNCeS

Cuzick J, Sestak I, Pinder SE, Ellis IO, Forsyth S, Bundred NJ, et al. Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial. Lancet Oncol. 2011;12:21-9. https://dx.doi.org/10.1016%2FS1470-2045(10)70266-7

Emdin SO, Granstrand B, Ringberg A, Sandelin K, Arnesson LG, Nordgren H, et al. SweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening. Acta Oncol. 2006;45:536-43. https://doi. org/10.1080/02841860600681569

Wärnberg F, Garmo H, Emdin S, Hedberg V, Adwall L, Sandelin K, et al. Effect of radiotherapy after breast-conserving surgery for ductal carcinoma in situ: 20 years follow-up in the randomized SweDCIS Trial. J Clin Oncol. 2014;32:3613-8. https://doi.org/10.1200/JCO.2014.56.2595

McCormick B, Winter K, Hudis C, Kuerer HM, Rakovitch E, Smith BL, et al. RTOG 9804: A Prospective Randomized Trial for Good-Risk Ductal Carcinoma In Situ Comparing Radiotherapy With Observation. J Clin Oncol. 2015;33(7):709- 15. https://doi.org/10.1200/JCO.2014.57.9029

Early Breast Cancer Trialists’ Collaborative Group, Correa C, McGale P, Taylor C, Wang Y, Clarke M, et al. Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast. J Natl Cancer Inst Monogr. 2010;2010:162-77. https://doi.org/10.1093/jncimonographs/lgq039

Goodwin A, Parker S, Ghersi D, Wilcken N. Post-operative radiotherapy for ductal carcinoma in situ of the breast. Cochrane Database Syst Rev. 2013;11:CD000563. https://doi. org/10.1002/14651858.CD000563.pub7

Bartelink H, Maingon P, Poortmans P, Weltens C, Fourquet A, Jager J, et al. Whole-breast irradiation with or without a boost for patients treated with breast-conserving surgery for early breast cancer: 20- year follow-up of a randomised phase 3 trial. Lancet Oncol. 2015 Jan;16(1):47-56. https://doi.org/10.1016/S1470-2045(14)71156-8

Omlin A, Amichetti M, Azria D, Cole BF, Fourneret P, Poortmans P, et al. Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network. Lancet Oncol. 2006;7:652-6. https:// doi.org/10.1016/S1470-2045(06)70765-3

Alvarado R, Lari SA, Roses RE, Smith BD, Yang W, Mittendorf EA, et al. Biology, treatment, and outcome in very young and older women with DCIS. Ann Surg Oncol. 2012;19:3777-84. https://dx.doi.org/10.1245%2Fs10434-012-2413-4

Halasz LM, Sreedhara M, Chen YH, Bellon JR, Punglia RS, Wong JS, et al. Improved outcomes of breast-conserving therapy for patients with ductal carcinoma in situ. Int J Radiat Oncol Biol Phys. 2012;82:e581-6. https://doi.org/10.1016/j.ijrobp.2011.08.015

Rakovitch E, Narod SA, Nofech-Moses S, Hanna W, Thiruchelvam D, Saskin R, et al. Impact of boost radiation in the treatment of ductal carcinoma in situ: a populationbased analysis. Int J Radiat Oncol Biol Phys. 2013;86:491-7. https://doi.org/10.1016/j.ijrobp.2013.02.031

Meattini I, Livi L, Franceschini D, Saieva C, Meacci F, Marrazzo L, et al. Role of radiotherapy boost in women with ductal carcinoma in situ: a single-center experience in a series of 389 patients. Eur J Surg Oncol. 2013;39:613-8. https://doi.org/10.1016/j.ejso.2013.03.002

Haviland JS, Owen JR, Dewar JA, Agrawal RK, Barrett J, Barrett- Lee PJ, et al. The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials. Lancet Oncol. 2013;14:1086- 94. https://doi.org/10.1016/S1470-2045(13)70386-3

Whelan TJ, Pignol JP, Levine MN, Julian JA, MacKenzie R, Parpia S, et al. Long-term results of hypofractionated radiation therapy for breast cancer. N Engl J Med. 2010;362:513-20. https://doi.org/10.1056/NEJMoa0906260

Nilsson C, Valachis A. The role of boost and hypofractionation as adjuvant radiotherapy in patients with DCIS: A meta-analysis of observational studies. Radiother Oncol. 2015;114(1):50-5. https://doi.org/10.1016/j.radonc.2015.01.001

Cutuli B, Lemanski C, Fourquet A, Lafontan B, Giard S, Meunier A, et al. Breast-conserving surgery with or without radiotherapy vs mastectomy for ductal carcinoma in situ: French Survey experience. Br J Cancer. 2009;100:1048-54. https://dx.doi.org/10.1038%2Fsj.bjc.6604968

Hughes KS, Schnaper LA, Berry D, Cirrincione C, McCormick B, Shank B, et al. Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med. 2004;351:971-7. https://doi.org/10.1056/NEJMoa040587

Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM. Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial. Lancet Oncol. 2015;16(3):266-73. https://doi.org/10.1016/S1470- 2045(14)71221-5

Smith BD, Gross CP, Smith GL, Galusha DH, Bekelman JE, Haffty BG. Effectiveness of radiation therapy for older women with early breast cancer. J Natl Cancer Inst. 2006;98:681-90. https:// doi.org/10.1093/jnci/djj186

Biganzoli L, Wildiers H, Oakman C, Marotti L, Loibl S, Kunkler I, et al. Management of elderly patients with breast cancer: updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA). Lancet Oncol. 2012;13:e148-60. https://doi.org/10.1016/ S1470-2045(11)70383-7

Marta GN, Macedo CR, Carvalho H de A, Hanna SA, da Silva JL, Riera R. Accelerated partial irradiation for breast cancer: systematic review and meta-analysis of 8653 women in eight randomized trials. Radiother Oncol. 2015;114:42-9. https://doi. org/10.1016/j.radonc.2014.11.014 31. Correa C, Harris EE, Leonardi MC, Smith BD, Taghian AG, Thompson AM, et al. Accelerated Partial Breast Irradiation: Executive summary for the update of an ASTRO Evidence-Based Consensus Statement. Pract Radiat Oncol. 2017;7:73-9. https://doi.org/10.1016/j.prro.2016.09.007

Hepel JT, Arthur D, Shaitelman S, Polgár C, Todor D, Zoberi I, et al. American Brachytherapy Society consensus report for accelerated partial breast irradiation using interstitial multicatheter brachytherapy. Brachytherapy. 2017;16(5):919- 28. https://doi.org/10.1016/j.brachy.2017.05.012

Polgár C, Van Limbergen E, Pötter R, Kovács G, Polo A, Lyczek J, et al. Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: recommendations of the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009). Radiother Oncol. 2010;94:264-73. https://doi.org/10.1016/j. radonc.2010.01.014

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Published

2018-10-28

How to Cite

Marta, G. N., & Carvalho, H. de A. (2018). RADIOTHERAPY IN BREAST DUCTAL CARCINOMA IN SITU. Mastology, 28(4), 251–256. Retrieved from https://revistamastology.emnuvens.com.br/revista/article/view/928

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Section

Review Articles