Epidemiology of breast cancer in a tertiary oncology hospital in the countryside of Minas Gerais
DOI:
https://doi.org/10.29289/2594539420230040%20Palavras-chave:
breast neoplasms, epidemiology, trendsResumo
Objective: In Brazil, the characteristics of breast cancer patients who arrive at cancer treatment services are influenced by conditions related to the tumor, to the diagnostic system and navigation in the phase prior to care, with regional differences being little known as well as their seasonal variation. Methods: This is a retrospective study of epidemiological data of patients with breast cancer treated at the Hospital do Câncer de Muriaé (HCM), an exclusively oncology hospital (CACON II), with primarily public care, a reference for cancer treatment in the east of Zona da Mata region, Minas Gerais. Clinical and care-related characteristics were evaluated from 2010 to 2021. Results: During this period, 4,573 new patients were treated. The care was primarily public (80.5%) and most patients were undiagnosed (45.7%) or untreated (71.8%) at the first visit. The patients were between 40 and 69 years old (70.2%) and a significant portion were between 70 and 74 years old (7.4%). The rate of early stage (clinical stage – CS 0 + I) represented only 33.9 and 25.8% of all patients and those treated exclusively in the hospital, respectively. There was no change in clinical stage and age group over the years. Conclusion: When evaluating epidemiological data, the characteristics of the service and the pre-institutional diagnostic care network should be analyzed, facts that influence the results. Throughout the period, there was no great variation in relation to age group and staging. In this region, the early stage of breast cancer has unsatisfactory rates, and the 70 to 74 age group should be considered in mammographic screening. Epidemiological studies are essential to improve health strategies.
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1. Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Nikšić M, et al. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018;391(10125):1023-75. https://doi.org/10.1016/S0140-6736(17)33326-3
2. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49. https://doi.org/10.3322/caac.21660
3. Berry DA, Cronin KA, Plevritis SK, Fryback DG, Clarke L, Zelen M, et al. Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med. 2005;353(17):1784-92. https://doi.org/10.1056/NEJMoa050518
4. Gøtzsche PC, Jørgensen KJ. Screening for breast cancer with mammography. Cochrane Database Syst Rev. 2013;2013(6):CD001877. https://doi.org/10.1002/14651858.CD001877.pub5
5. Vieira RA, Uemura G, Zucca-Matthes G, Costa AM, Micheli RA, Oliveira CZ. Evaluating breast cancer health system between countries: the use of USA/SEER and Brazilian women as a cohort sample. Breast J. 2015;21(3):322-3. https://doi.org/10.1111/tbj.12410
6. da Costa Vieira RA, Biller G, Uemura G, Ruiz CA, Curado MP. Breast cancer screening in developing countries. Clinics (Sao Paulo). 2017;72(4):244-53. https://doi.org/10.6061/clinics/2017(04)09
7. Perry N, Broeders M, de Wolf C, Tornberg S, Holland R, von Karsa L. European guidelines for quality assurance in breast cancer screening and diagnosis. Fourth edition--summary document. Ann Oncol. 2008;19(4):614-22. https://doi.org/10.1093/annonc/mdm481
8. Vieira RAC, Formenton A, Bertolini SR. Breast cancer screening in Brazil. Barriers related to the health system. Rev Assoc Med Bras (1992). 2017;63(5):466-74. https://doi.org/10.1590/1806-9282.63.05.466
9. Tsunoda AT, Nunes JS, Watanabe APHU, Santos-Junior LA, Maudad EC, Brentani RR. Controle de qualidade em ratreamento mamográfico no Brasil: experiência do Hospital de Câncer de Barretos. Rev Bras Mastologia. 2013;23(1):12-8.
10. Carvalho FM, Bacchi LM, Pincerato KM, Van de Rijn M, Bacchi CE. Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil. BMC Women's Health. 2014;14:102. https://doi.org/10.1186/1472-6874-14-102
11. da Costa Vieira RA, Sant'Anna D, Laus AC, Bacchi CE, Silva RJC, Oliveira-Junior I, et al. Genetic Ancestry of 1127 Brazilian Breast Cancer Patients and its correlation with molecular subtype and Geographic Region. Clin Breast Cancer. 2023;23(5):527-37. https://doi.org/10.1016/j.clbc.2023.04.001
12. Makdissi FB, Leite FPM, Peres SV, Silva DRM, Oliveira MM, Lopez RVM, et al. Breast cancer survival in a Brazilian Cancer Center: a cohort study of 5,095 patients. Mastology. 2019;29(1):37-46. https://doi.org/10.29289/2594539420190000437
13. Medeiros JM, Linhares JC, Hatschbach SBB, Hubie DP, Rahman AS, Orlandi D, et al. Perfil epidemiológico e estudo de sobrevida dos pacientes com câncer de mama atendidos no Hospital Erasto Gaertner em Curitiba, PR. Rev Bras Mastologia. 2016;26(3):107-12. https://doi.org/10.5327/Z201600030005RBM
14. Laila HJEA, Zenkner JRG, Araujo MC, Becker JDL, Pereira AD. Characterization of prognostic factors of breast cancer among women with this condition attended by the Brazilian Unified Health System in the municipality of Bagé, Rio Grande do Sul, Brazil. Mastology. 2019;2(29):64-70. https://doi.org/10.29289/2594539420190000438
15. Brasil. Ministério da Saúde. Gabinete do Ministro. Portaria no 3.535 de 2 de setembro de 1998. Estabelece critérios para cadastramento de centros de atendimento em oncologia. Brasília: Ministerio da Saúde; 1998 [cited on 2023 Sept 30]. Available from: https://bvsms.saude.gov.br/bvs/saudelegis/gm/1998/prt3535_02_09_1998_revog.html
16. Nunes BAP, Siqueira SL, Pereira SM, Pacheco TJ, Pessanha TO, Mendonça SB. Perfil epidemiológico dos pacientes diagnosticados com câncer de mama em Campos dos Goytacazes (RJ), Brazil. Rev Bras Mastologia. 2012;22(4):117-23.
17. Haddad CF, Reias CM, Paiva ACO, Pereira AO, Leal PH, Reis SMC, et al. Evaluation of clinical, pathological and epidemiological profile of patients with breast cancer in the microregion of Lavras – MG. Mastology. 2023;33:e20220037. https://doi.org/10.29289/2594539420220037
18. Haddad CF. Características clínico-patológicas e estadiamendo ao diagnóstico de pacientes com câncer de mama em um centro de saúde do interior de Minas Gerais. Rev Bras Mastologia. 2014;24(4):103-8. https://doi.org/10.5327/Z201400040003RBM
19. Barboza RS, Ferreira JKR, Faustino RS, Silveira Junior LS. Breast cancer in Rio Grande do Norte, a retrospetive study: epidemiological, clinical and therapeutic profile. Mastology. 2017;27(2):109-16. https://doi.org/10.5327/Z2594539420170000174
20. Renna-Junior NL, Silva GA. Late-stage diagnosis of breast cancer in Brazil: analysis of data from Hospital-Based Cancer Registries (2000–2012). Rev Bras Ginecol Obstret. 2018;40(3):127-36. https://doi.org/10.1055/s-0038-1624580
21. Rocha AFBM, Freitas-Junior R, Ferreira GLR, Rodrigues DCN, Rahal RMS. COVID-19 and breast cancer in Brazil. Int J Pub Health. 2023;68:160585. https://doi.org/10.3389/ijph.2023.1605485
22. Oliveira-Junior I, Mauad EC, Fonseca BO, Watanabe AHU, Vieira RAC. Late results of regional breast cancer screening progam performed in the interior of São Paulo State, Brazil. Mastology. 2018;28(Suppl 1):7. https://doi.org/10.29289/259453942018V28S1009
23. Mattos JSC, Caleffi M, Vieira RAC. Rastreamento mamográfico no Brasil: resultados preliminares. Rev Bras Mastologia. 2013;23(1):22-7.
24. Rosa DD, Bines J, Werutsky G, Barrios CH, Cronemberger E, Queiroz GS, et al. The impact of sociodemographic factors and health insurance coverage in the diagnosis and clinicopathological characteristics of breast cancer in Brazil: AMAZONA III study (GBECAM 0115). Breast Cancer Res Treat. 2020;183(3):749-57. https://doi.org/10.1007/s10549-020-05831-y
25. Registro Hospitalar do Câncer do Hospital de Câncer de Barretos. Infographics [Internet]. 2022 [cited on 2023 Sept 30]. Available from: https://infogram.com/rhc_hcb
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Copyright (c) 2024 Luiz Carlos Navarro de Oliveira, Sebastião Maurício de Oliveira Castro, Carla Simone Moreira de Freitas, Rita de Cássia de Jesus Duarte Silva, Flávio Ferraz Vieira, Rodrigo Bastos Tostes, Bruno Licy Gomes de Melo, René Aloisio da Costa Vieira
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
