Primary breast angiosarcoma: a diagnostic challenge

Abstract

The authors display a case of a woman aged 57 years who presented a palpable mass in the right breast. The mammography revelled a focal asymmetry, with no suspicious findings on ultrasound. Breast MRI showed an irregular and undefined mass with low signal intensity on T1 without fat suppression and high signal on T2‑weighted fat-suppressed, with irregular heterogeneous enhancement with thick enhancement septa, fast initial kinetic enhancement and persistent type curve, measuring 5.3 cm. A new ultrasound exam was performed, observing hypoechoic nodule of 1.2 cm associated with changes in echogenicity of the adjacent breast parenchyma. Ultrasound‑guided vacuum biopsy of the hypoechoic nodule and the adjacent parenchyma was performed. Histopathological study showed primary breast angiosarcoma of low‑grade. The PET‑CT performed six months after surgery showed no recurrence or metastasis.